Noviocell BV is a highly innovative biotech company. It focuses on the development of the first ever synthetic solution for 3D cell culturing, ranging from organoid growth to personalized medicine.
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Researchers at Maastricht University, Noviocell BV and Cell Guidance Systems Ltd are collaborating on an EU funded Eurostars project to develop fully-defined matrices for the 3D culture of organoids.
Complex diseases like cancer are more frequently being modelled using in vitro systems as more researchers opt for three-dimensional (3D) cell culture methods over two-dimensional (2D) ones. In some cases, 3D systems even have advantages over tumour xenograft models .
Cell biologists are slowly replacing two-dimensional (2D) cell culture with more advanced alternatives, such as growing cells in three-dimensions (3D) by their encapsulation in hydrogels. Unlike 2D cell culture, where cells adhere to the culture vessel’s flat, hard surfaces in monolayers, 3D systems facilitate a higher order of cellular spatial organization and thus yield more physiologically relevant information – a definite advantage if you are looking to put a potential therapeutic molecule through its paces.